The announcement will be made at the base of the historic building Thursday morning.
What city officials are calling "a major announcement", is expected to be made at 10am Thursday on the future of the Carlisle Building.
A press release sent-out Wednesday says the announcement will be made in front of the historic structure, which has been sitting idle since a 2003 arson fire heavily damaged the building.
Chillicothe Mayor Jack Everson will be joined at the announcement by Adena Health Systems CEO Mark Shuter, Marvin Jones of the Chamber of Commerce, Joe Molnar of Huntington Bank and a representative of the Chesler Group- which deals with preservation of historic structures.